Go
A senior regulatory affairs opportunity is open in Johannesburg for a pharmacist who can lead product registrations and keep a pharmaceutical portfolio compliant with South African law. Advertised by Hire Resolve on behalf of a leading South African pharmaceutical company, this Senior Regulatory Affairs Pharmacist role suits an experienced professional with strong technical knowledge, leadership capability and a solid understanding of pharmaceutical regulatory requirements.
Hire Resolve is the recruitment agency behind this vacancy. The agency describes itself as a top recruitment agency in South Africa, connecting businesses with skilled and experienced professionals across a wide range of industries and locations, and helping companies with hiring staff and finding the right talent for their workforce requirements. The employer is a leading South African pharmaceutical company based in Johannesburg. The role focuses on managing regulatory activities, overseeing product registrations and lifecycle management, ensuring compliance with South African Health Products Regulatory Authority (SAHPRA) requirements, and providing technical guidance and support to the regulatory affairs team.
The successful candidate will be responsible for managing regulatory submissions, maintaining product registrations, engaging with regulatory authorities, and supporting cross-functional business activities. The duties include ensuring compliance with SAHPRA legislation, the Medicines and Related Substances Act, the Pharmacy Act and applicable regulatory guidelines. The pharmacist compiles, reviews and submits common technical document and electronic common technical document (CTD/eCTD) regulatory dossiers for registrations, variations, renewals and related applications, although the wording of that point is cut off in the source view, so applicants should check the original advert for the complete wording.
Day to day, the role involves coordinating responses to SAHPRA queries and deficiency letters within agreed timelines, and managing product lifecycle activities, including product information and patient information leaflet updates, labelling changes and approved variations. The pharmacist maintains accurate regulatory records, submission trackers and document management systems, and builds and maintains effective relationships with SAHPRA and other regulatory authorities. Regulatory support is also provided for new product launches, marketing materials, packaging and business development activities, and the pharmacist collaborates with marketing, supply chain, manufacturing and new business development teams on regulatory matters.
At senior level, the role includes mentoring and providing technical guidance to regulatory affairs team members, supporting workload planning, prioritisation and departmental objectives, monitoring submission timelines and identifying opportunities to improve regulatory processes, systems and ways of working, and identifying and escalating regulatory risks and compliance issues where appropriate.
The listing states that a Bachelor of Pharmacy (B.Pharm) degree and current registration with the South African Pharmacy Council (SAPC) are required, together with a minimum of five years of regulatory affairs experience within the pharmaceutical industry. Candidates need demonstrated experience mentoring, coaching or leading regulatory affairs team members or projects, sound knowledge of SAHPRA requirements, CTD/eCTD submissions and product lifecycle management, and a proven ability to independently compile and submit regulatory dossiers and manage regulatory authority interactions, although the wording of that last point is cut off in the source view. Experience with DocuBridge, eCTD or equivalent regulatory document management systems is also required.
Beyond the formal requirements, the listing asks for strong technical regulatory knowledge, excellent planning, organisational and communication skills, strong stakeholder management, analytical thinking and sound judgement, high levels of accountability and attention to detail, and a collaborative approach with a commitment to continuous improvement. The salary is stated in the listing as R8,300 – R100,000 per month, a very wide range that is recorded here exactly as stated, and the position is permanent at senior level. The listing was posted on 28 October 2026 and is shown as expiring in 22 days.
This vacancy is advertised on CareerJunction by Hire Resolve, and the Apply button on this page opens the original CareerJunction listing. The listing itself notes that applications can also be made by email or via LinkedIn, and that the Hire Resolve website lists further opportunities. Apply only through the original advert or the agency’s own channels, and be cautious of anyone who contacts you outside those channels asking for payment or personal banking details in exchange for a job offer. A genuine recruiter will not ask you to pay to secure an interview or a placement.
Before applying, gather evidence that matches the senior, hands-on nature of this role. Prepare examples of dossiers you have compiled and submitted independently, SAHPRA queries you have resolved within deadline, and product lifecycle changes you have managed, such as labelling updates or patient information leaflet revisions. If you have mentored junior regulatory colleagues or led a regulatory project, describe the team, the timelines and the outcome. Candidates should make their B.Pharm qualification and current SAPC registration easy to find, and mention their experience with DocuBridge, eCTD or equivalent systems explicitly, since the listing names those tools.
Applications are made through the original CareerJunction listing, where Hire Resolve reviews submissions against the stated requirements. Shortlisted candidates can expect to discuss their regulatory submissions experience, their knowledge of SAHPRA processes, and their leadership experience within a regulatory affairs team. Because the role supports launches, marketing materials and packaging, interviewers may also explore how the candidate has worked with marketing, supply chain and manufacturing colleagues on regulatory questions.
This page is for information only and is not the employer or the recruiter. Details such as the salary range, requirements and duties are taken from the listing as shown, and some listing wording is cut off in the source view, so readers should check the original advert for complete wording before applying. The stated salary range of R8,300 – R100,000 per month is unusually wide and is reproduced exactly as shown in the listing; the final offer is a matter for the employer and the agency.
#SouthAfricaJobs #JobsInSouthAfrica #PharmacistJobs #RegulatoryAffairsJobs #PharmaceuticalJobs #HealthcareJobs #JohannesburgJobs #GautengJobs
This listing was originally posted by Hire Resolve — your application opens on their original job advert.
Apply on Hire Resolve's website →